β-Hydroxybutyrate upregulates FGF21 expression through inhibition of histone deacetylases in hepatocytes

Fibroblast growth factor 21 (FGF21) is secreted by hepatocytes as a peptide hormone to regulate glucose and lipid metabolism. FGF21 promotes hepatic ketogenesis and increases ketone body utilization in starvation. Histones are the target molecules of nutrients in regulating hepatic metabolic homeost...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Aili, Zhao, Yanyan, Zhang, Lijun, Liang, Xiangyan, Zhang, Xiaochun, Liang, Fenli, Nian, Shen, Li, Xinhua, Sun, Zhuo, Li, Ke, Zhao, Yu-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372706/
https://www.ncbi.nlm.nih.gov/pubmed/36045720
http://dx.doi.org/10.1515/biol-2022-0095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372706/
https://www.ncbi.nlm.nih.gov/pubmed/36045720
http://dx.doi.org/10.1515/biol-2022-0095

Ejemplares similares