Drug‐microenvironment perturbations reveal resistance mechanisms and prognostic subgroups in CLL

The tumour microenvironment and genetic alterations collectively influence drug efficacy in cancer, but current evidence is limited and systematic analyses are lacking. Using chronic lymphocytic leukaemia (CLL) as a model disease, we investigated the influence of 17 microenvironmental stimuli on 12...

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Detalles Bibliográficos
Autores principales: Bruch, Peter‐Martin, Giles, Holly AR, Kolb, Carolin, Herbst, Sophie A, Becirovic, Tina, Roider, Tobias, Lu, Junyan, Scheinost, Sebastian, Wagner, Lena, Huellein, Jennifer, Berest, Ivan, Kriegsmann, Mark, Kriegsmann, Katharina, Zgorzelski, Christiane, Dreger, Peter, Zaugg, Judith B, Müller‐Tidow, Carsten, Zenz, Thorsten, Huber, Wolfgang, Dietrich, Sascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372727/
https://www.ncbi.nlm.nih.gov/pubmed/35959629
http://dx.doi.org/10.15252/msb.202110855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372727/
https://www.ncbi.nlm.nih.gov/pubmed/35959629
http://dx.doi.org/10.15252/msb.202110855

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