Cargando…
Targeting the lung epithelium after intravenous delivery by directed evolution of underexplored sites on the AAV capsid
Advances in adeno-associated virus (AAV) engineering have provided exciting new tools for research and potential solutions for gene therapy. However, the lung has not received the same tailored engineering as other major targets of debilitating genetic disorders. To address this, here we engineered...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372736/ https://www.ncbi.nlm.nih.gov/pubmed/35990749 http://dx.doi.org/10.1016/j.omtm.2022.07.010 |