Elucidating the mechanism of nucleation inhibition of pathology crystallization of gout based on the evidence from amorphous form and in solution

The first gout attack in a hyperuricaemic patient may be regarded as a nucleation event which is caused by monosodium urate monohydrate (MSUM) deposition in the synovial fluid. The effect of Tailor-Made Inhibition (TMI) may be effective as drugs for the prevention of aberrant nucleation and crystall...

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Detalles Bibliográficos
Autores principales: Zhou, Dan, Jiao, Shiqi, Zhang, Pengfei, Jin, Yige, Pan, Yonglan, Ou, Chunyan, Zhang, Xingde, Fu, Tingming, Liu, Yonghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372821/
https://www.ncbi.nlm.nih.gov/pubmed/36106008
http://dx.doi.org/10.1039/d2ra03289a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372821/
https://www.ncbi.nlm.nih.gov/pubmed/36106008
http://dx.doi.org/10.1039/d2ra03289a

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