A hierarchy of selection pressures determines the organization of the T cell receptor repertoire

We systematically examine the receptor repertoire in T cell subsets in young, adult, and LCMV-infected mice. Somatic recombination generates diversity, resulting in the limited overlap between nucleotide sequences of different repertoires even within the same individual. However, statistical feature...

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Detalles Bibliográficos
Autores principales: Mark, Michal, Reich-Zeliger, Shlomit, Greenstein, Erez, Reshef, Dan, Madi, Asaf, Chain, Benny, Friedman, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372880/
https://www.ncbi.nlm.nih.gov/pubmed/35967295
http://dx.doi.org/10.3389/fimmu.2022.939394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372880/
https://www.ncbi.nlm.nih.gov/pubmed/35967295
http://dx.doi.org/10.3389/fimmu.2022.939394

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