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Development of a human antibody that exhibits antagonistic activity toward CC chemokine receptor 7

BACKGROUND: CC chemokine receptor 7 (CCR7) is a member of G-protein-coupled receptor family and mediates chemotactic migration of immune cells and different cancer cells induced via chemokine (C–C motif) ligand 19 (CCL19) or chemokine (C–C motif) ligand 21 (CCL21). Hence, the identification of block...

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Detalles Bibliográficos
Autores principales: Jang, Moon-Sung, Ismail, Nurain Syahirah Binti, Yu, Yeon Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372883/
https://www.ncbi.nlm.nih.gov/pubmed/35967907
http://dx.doi.org/10.1093/abt/tbac016