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Development of a human antibody that exhibits antagonistic activity toward CC chemokine receptor 7
BACKGROUND: CC chemokine receptor 7 (CCR7) is a member of G-protein-coupled receptor family and mediates chemotactic migration of immune cells and different cancer cells induced via chemokine (C–C motif) ligand 19 (CCL19) or chemokine (C–C motif) ligand 21 (CCL21). Hence, the identification of block...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372883/ https://www.ncbi.nlm.nih.gov/pubmed/35967907 http://dx.doi.org/10.1093/abt/tbac016 |