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WNT4 overexpression and secretion in thymic epithelial tumors drive an autocrine loop in tumor cells in vitro
BACKGROUND: WNT4-driven non-canonical signaling is crucial for homeostasis and age-related involution of the thymus. Abnormal WNT signaling is important in many cancers, but the role of WNT signaling in thymic tumors is largely unknown. MATERIALS & METHODS: Expression and function of WNT4 and FZ...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372913/ https://www.ncbi.nlm.nih.gov/pubmed/35965500 http://dx.doi.org/10.3389/fonc.2022.920871 |