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WNT4 overexpression and secretion in thymic epithelial tumors drive an autocrine loop in tumor cells in vitro

BACKGROUND: WNT4-driven non-canonical signaling is crucial for homeostasis and age-related involution of the thymus. Abnormal WNT signaling is important in many cancers, but the role of WNT signaling in thymic tumors is largely unknown. MATERIALS & METHODS: Expression and function of WNT4 and FZ...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaonan, Schalke, Berthold, Kvell, Krisztian, Kriegsmann, Katharina, Kriegsmann, Mark, Graeter, Thomas, Preissler, Gerhard, Ott, German, Kurz, Katrin, Bulut, Elena, Ströbel, Philipp, Marx, Alexander, Belharazem, Djeda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372913/
https://www.ncbi.nlm.nih.gov/pubmed/35965500
http://dx.doi.org/10.3389/fonc.2022.920871