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PIKfyve-specific inhibitors restrict replication of multiple coronaviruses in vitro but not in a murine model of COVID-19

The ongoing COVID-19 pandemic has claimed more than 6 million lives and continues to test the world economy and healthcare systems. To combat this pandemic, the biological research community has shifted efforts to the development of medical countermeasures, including vaccines and therapeutics. Howev...

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Detalles Bibliográficos
Autores principales: Logue, James, Chakraborty, Arup R., Johnson, Robert, Goyal, Girija, Rodas, Melissa, Taylor, Louis J., Baracco, Lauren, McGrath, Marisa E., Haupt, Robert, Furlong, Brooke A., Soong, Mercy, Prabhala, Pranav, Horvath, Viktor, Carlson, Kenneth E., Weston, Stuart, Ingber, Donald E., DePamphilis, Melvin L., Frieman, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372968/
https://www.ncbi.nlm.nih.gov/pubmed/35962188
http://dx.doi.org/10.1038/s42003-022-03766-2