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Increased Breadth of Group A Streptococcus Antibody Responses in Children With Acute Rheumatic Fever Compared to Precursor Pharyngitis and Skin Infections( )

BACKGROUND: Group A Streptococcus (GAS) causes superficial pharyngitis and skin infections as well as serious autoimmune sequelae such as acute rheumatic fever (ARF) and subsequent rheumatic heart disease. ARF pathogenesis remains poorly understood. Immune priming by repeated GAS infections is thoug...

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Detalles Bibliográficos
Autores principales: Whitcombe, Alana L, McGregor, Reuben, Bennett, Julie, Gurney, Jason K, Williamson, Deborah A, Baker, Michael G, Moreland, Nicole J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373162/
https://www.ncbi.nlm.nih.gov/pubmed/35134931
http://dx.doi.org/10.1093/infdis/jiac043