Mitochondrial ROS drive resistance to chemotherapy and immune-killing in hypoxic non-small cell lung cancer

BACKGROUND: Solid tumors subjected to intermittent hypoxia are characterized by resistance to chemotherapy and immune-killing by effector T-lymphocytes, particularly tumor-infiltrating Vγ9Vδ2 T-lymphocytes. The molecular circuitries determining this double resistance are not known. METHODS: We analy...

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Detalles Bibliográficos
Autores principales: Salaroglio, Iris C., Belisario, Dimas Carolina, Akman, Muhlis, La Vecchia, Sofia, Godel, Martina, Anobile, Dario Pasquale, Ortone, Giacomo, Digiovanni, Sabrina, Fontana, Simona, Costamagna, Costanzo, Rubinstein, Menachem, Kopecka, Joanna, Riganti, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373288/
https://www.ncbi.nlm.nih.gov/pubmed/35953814
http://dx.doi.org/10.1186/s13046-022-02447-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373288/
https://www.ncbi.nlm.nih.gov/pubmed/35953814
http://dx.doi.org/10.1186/s13046-022-02447-6

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