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Infusion of two-dose mesenchymal stem cells is more effective than a single dose in a dilated cardiomyopathy rat model by upregulating indoleamine 2,3-dioxygenase expression

BACKGROUND AND AIMS: The therapeutic efficacy of single-dose mesenchymal stromal cell (MSC) therapy for heart failure (HF) remains inconsistent. This study aimed to investigate whether infusion with two-dose human umbilical cord MSC (hUCMSCs) could be therapeutically superior to single-dose therapy...

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Detalles Bibliográficos
Autores principales: Gong, Chenyi, Chang, Lei, Sun, Xuan, Qi, Yu, Huang, Rong, Chen, Ke, Wang, Bin, Kang, Lina, Wang, Lian, Xu, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373305/
https://www.ncbi.nlm.nih.gov/pubmed/35962420
http://dx.doi.org/10.1186/s13287-022-03101-w