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Melatonin ameliorates diabetic hyperglycaemia-induced impairment of Leydig cell steroidogenic function through activation of SIRT1 pathway

BACKGROUND: Diabetes mellitus (DM)-related complications are important health problems worldwide. The underlying mechanisms for diabetic male subfertility/infertility are considerably complicated and need to be unveiled for therapeutic intervention. Melatonin treatment was investigated to assess the...

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Detalles Bibliográficos
Autores principales: Wang, Ping, Zhang, Shoubing, Lin, Shuai, Lv, Zhengmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373359/
https://www.ncbi.nlm.nih.gov/pubmed/35962432
http://dx.doi.org/10.1186/s12958-022-00991-6