GPX4 suppresses ferroptosis to promote malignant progression of endometrial carcinoma via transcriptional activation by ELK1

BACKGROUND: Glutathione Peroxidase 4 (GPX4) is a key protein that inhibits ferroptosis. However, its biological regulation and mechanism in endometrial cancer (EC) have not been reported in detail. METHODS: The expression of GPX4 in EC tissues was determined by TCGA databases, qRT-PCR, Western blot,...

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Detalles Bibliográficos
Autores principales: Wei, Sitian, Yu, Zhicheng, Shi, Rui, An, Lanfen, Zhang, Qi, Zhang, Qian, Zhang, Tangansu, Zhang, Jun, Wang, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373394/
https://www.ncbi.nlm.nih.gov/pubmed/35962333
http://dx.doi.org/10.1186/s12885-022-09986-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373394/
https://www.ncbi.nlm.nih.gov/pubmed/35962333
http://dx.doi.org/10.1186/s12885-022-09986-3

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