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The CHAMP-study: the CHemopreventive effect of lithium in familial AdenoMatous Polyposis; study protocol of a phase II trial

BACKGROUND: Familial adenomatous polyposis (FAP) is a rare autosomal dominant disease characterized by germline mutations in the Adenomatous Polyposis Coli (APC) gene, resulting in the development of numerous colorectal adenomas. As these patients have a high risk of developing colorectal cancer (CR...

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Detalles Bibliográficos
Autores principales: Linssen, Jasmijn D. G., van Neerven, Sanne M., Aelvoet, Arthur S., Elbers, Clara C., Vermeulen, Louis, Dekker, Evelien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373414/
https://www.ncbi.nlm.nih.gov/pubmed/35962368
http://dx.doi.org/10.1186/s12876-022-02442-3