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GPCR kinases generate an APH1A phosphorylation barcode to regulate amyloid-β generation
Emerging evidence suggests that G protein-coupled receptor (GPCR) kinases (GRKs) are associated with the pathophysiology of Alzheimer’s disease (AD). However, GRKs have not been directly implicated in regulation of the amyloid-β (Aβ) pathogenic cascade in AD. Here, we determine that GRKs phosphoryla...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373432/ https://www.ncbi.nlm.nih.gov/pubmed/35858570 http://dx.doi.org/10.1016/j.celrep.2022.111110 |