Exploring mutation specific beta blocker pharmacology of the pathogenic late sodium channel current from patient-specific pluripotent stem cell myocytes derived from long QT syndrome mutation carriers

The congenital long QT syndrome (LQTS), one of the most common cardiac channelopathies, is characterized by delayed ventricular repolarization underlying prolongation of the QT interval of the surface electrocardiogram. LQTS is caused by mutations in genes coding for cardiac ion channels or ion chan...

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Detalles Bibliográficos
Autores principales: Comollo, Thomas W., Zou, Xinle, Zhang, Chuangeng, Kesters, Divya, Hof, Thomas, Sampson, Kevin J., Kass, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373745/
https://www.ncbi.nlm.nih.gov/pubmed/35949058
http://dx.doi.org/10.1080/19336950.2022.2106025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373745/
https://www.ncbi.nlm.nih.gov/pubmed/35949058
http://dx.doi.org/10.1080/19336950.2022.2106025

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