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Motif models proposing independent and interdependent impacts of nucleotides are related to high and low affinity transcription factor binding sites in Arabidopsis

Position weight matrix (PWM) is the traditional motif model representing the transcription factor (TF) binding sites. It proposes that the positions contribute independently to TFs binding affinity, although this hypothesis does not fit the data perfectly. This explains why PWM hits are missing in a...

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Detalles Bibliográficos
Autores principales: Tsukanov, Anton V., Mironova, Victoria V., Levitsky, Victor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373801/
https://www.ncbi.nlm.nih.gov/pubmed/35968123
http://dx.doi.org/10.3389/fpls.2022.938545