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RNA N(6)-methyladenosine reader YTHDC1 is essential for TGF-beta-mediated metastasis of triple negative breast cancer

RNA N(6)-methyladenosine (m(6)A) modification and its regulators fine tune gene expression and contribute to tumorigenesis. This study aims to uncover the essential role and the underlying molecular mechanism(s) of the m(6)A reader YTHDC1 in promoting triple negative breast cancer (TNBC) metastasis....

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Detalles Bibliográficos
Autores principales: Tan, Brandon, Zhou, Keren, Liu, Wei, Prince, Emily, Qing, Ying, Li, Yangchan, Han, Li, Qin, Xi, Su, Rui, Pokharel, Sheela Pangeni, Yang, Lu, Zhao, Zhicong, Shen, Chao, Li, Wei, Chen, Zhenhua, Zhang, Zheng, Deng, Xiaolan, Small, Andrew, Wang, Kitty, Leung, Keith, Chen, Chun-Wei, Shen, Binghui, Chen, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373808/
https://www.ncbi.nlm.nih.gov/pubmed/35966596
http://dx.doi.org/10.7150/thno.71872