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Conquering oncogenic KRAS and its bypass mechanisms

Aberrant activation of KRAS signaling is common in cancer, which has catalyzed heroic drug development efforts to target KRAS directly or its downstream signaling effectors. Recent works have yielded novel small molecule drugs with promising preclinical and clinical activities. Yet, no matter how a...

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Detalles Bibliográficos
Autores principales: Hou, Pingping, Wang, Y. Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373815/
https://www.ncbi.nlm.nih.gov/pubmed/35966590
http://dx.doi.org/10.7150/thno.71260