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Conquering oncogenic KRAS and its bypass mechanisms
Aberrant activation of KRAS signaling is common in cancer, which has catalyzed heroic drug development efforts to target KRAS directly or its downstream signaling effectors. Recent works have yielded novel small molecule drugs with promising preclinical and clinical activities. Yet, no matter how a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Ivyspring International Publisher
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373815/ https://www.ncbi.nlm.nih.gov/pubmed/35966590 http://dx.doi.org/10.7150/thno.71260 |