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Engineered extracellular vesicles with high collagen-binding affinity present superior in situ retention and therapeutic efficacy in tissue repair

Although stem cell-derived extracellular vesicles (EVs) have remarkable therapeutic potential for various diseases, the therapeutic efficacy of EVs is limited due to their degradation and rapid diffusion after administration, hindering their translational applications. Here, we developed a new gener...

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Detalles Bibliográficos
Autores principales: Hao, Dake, Lu, Lu, Song, Hengyue, Duan, Yixin, Chen, Jianing, Carney, Randy, Li, Jian Jian, Zhou, Ping, Nolta, Jan, Lam, Kit S., Leach, J. Kent, Farmer, Diana L, Panitch, Alyssa, Wang, Aijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373818/
https://www.ncbi.nlm.nih.gov/pubmed/35966577
http://dx.doi.org/10.7150/thno.70448