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Lipid phosphate phosphatase-2 promotes tumor growth through increased c-Myc expression

LPP2 is one of three enzymes in the lipid phosphate phosphatase family (LPP1-3) that dephosphorylate extracellular and intracellular bioactive lipid phosphates and pyrophosphates. LPP2 increases cell growth and LPP2 expression is elevated in a variety of malignancies, implying that LPP2 is a pro-tum...

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Detalles Bibliográficos
Autores principales: Tang, Xiaoyun, Cromwell, Christopher R., Liu, Rongzong, Godbout, Roseline, Hubbard, Basil P., McMullen, Todd P.W., Brindley, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373824/
https://www.ncbi.nlm.nih.gov/pubmed/35966578
http://dx.doi.org/10.7150/thno.66230