Age-Dependent Behavioral and Metabolic Assessment of App(NL−G−F/NL−G−F) Knock-in (KI) Mice

Mitochondria play a crucial role in Alzheimer's disease (AD) onset and progression. Traditional transgenic AD mouse models which were widely used in the past decades share a common limitation: The overexpression of APP and overproduction of amyloid-beta (Aβ) are accompanied by other APP peptide...

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Detalles Bibliográficos
Autores principales: Wang, Shanshan, Ichinomiya, Taiga, Savchenko, Paul, Devulapalli, Swetha, Wang, Dongsheng, Beltz, Gianna, Saito, Takashi, Saido, Takaomi C., Wagner, Steve L., Patel, Hemal H., Head, Brian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373872/
https://www.ncbi.nlm.nih.gov/pubmed/35966019
http://dx.doi.org/10.3389/fnmol.2022.909989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373872/
https://www.ncbi.nlm.nih.gov/pubmed/35966019
http://dx.doi.org/10.3389/fnmol.2022.909989

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