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A new perspective on NO pathway in sepsis and ADMA lowering as a potential therapeutic approach
The nitric oxide pathway plays a critical role in vascular homeostasis. Increased levels of systemic nitric oxide (NO) are observed in preclinical models of sepsis and endotoxemia. This has led to the postulation that vasodilation by inducible nitric oxide synthase (iNOS) generated NO may be a mecha...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373887/ https://www.ncbi.nlm.nih.gov/pubmed/35962414 http://dx.doi.org/10.1186/s13054-022-04075-0 |