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The Association Between Longevity-Associated FOXO3 Allele and Heart Disease in Septuagenarians and Octogenarians: The SONIC Study

The G allele of FOXO3 gene (single-nucleotide polymorphism; rs2802292) is strongly associated with human longevity. However, knowledge of the effect of FOXO3 in older populations, men or women, with heart disease is limited. This cross-sectional study in Japan included 1836 older adults in the 70- a...

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Detalles Bibliográficos
Autores principales: Klinpudtan, Nonglak, Allsopp, Richard C, Kabayama, Mai, Godai, Kayo, Gondo, Yasuyuki, Masui, Yukie, Akagi, Yuya, Srithumsuk, Werayuth, Sugimoto, Ken, Akasaka, Hiroshi, Takami, Yoichi, Takeya, Yasushi, Yamamoto, Koichi, Ikebe, Kazunori, Yasumoto, Saori, Ogawa, Madoka, Ishizaki, Tatsuro, Arai, Yasumichi, Rakugi, Hiromi, Chen, Randi, Willcox, Bradley J, Willcox, D Craig, Kamide, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373940/
https://www.ncbi.nlm.nih.gov/pubmed/34254639
http://dx.doi.org/10.1093/gerona/glab204