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The Association Between Longevity-Associated FOXO3 Allele and Heart Disease in Septuagenarians and Octogenarians: The SONIC Study
The G allele of FOXO3 gene (single-nucleotide polymorphism; rs2802292) is strongly associated with human longevity. However, knowledge of the effect of FOXO3 in older populations, men or women, with heart disease is limited. This cross-sectional study in Japan included 1836 older adults in the 70- a...
Autores principales: | Klinpudtan, Nonglak, Allsopp, Richard C, Kabayama, Mai, Godai, Kayo, Gondo, Yasuyuki, Masui, Yukie, Akagi, Yuya, Srithumsuk, Werayuth, Sugimoto, Ken, Akasaka, Hiroshi, Takami, Yoichi, Takeya, Yasushi, Yamamoto, Koichi, Ikebe, Kazunori, Yasumoto, Saori, Ogawa, Madoka, Ishizaki, Tatsuro, Arai, Yasumichi, Rakugi, Hiromi, Chen, Randi, Willcox, Bradley J, Willcox, D Craig, Kamide, Kei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373940/ https://www.ncbi.nlm.nih.gov/pubmed/34254639 http://dx.doi.org/10.1093/gerona/glab204 |
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