Zoledronate Extends Health Span and Survival via the Mevalonate Pathway in a FOXO-dependent Manner

Over recent decades, increased longevity has not been paralleled by extended health span, resulting in more years spent with multiple diseases in older age. As such, interventions to improve health span are urgently required. Zoledronate (Zol) is a nitrogen-containing bisphosphonate, which inhibits...

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Detalles Bibliográficos
Autores principales: Chen, Zhengqi, Cordero, Julia, Alqarni, Adel M, Slack, Cathy, Zeidler, Martin P, Bellantuono, Ilaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
THE JOURNAL OF GERONTOLOGY: Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373971/
https://www.ncbi.nlm.nih.gov/pubmed/34137822
http://dx.doi.org/10.1093/gerona/glab172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373971/
https://www.ncbi.nlm.nih.gov/pubmed/34137822
http://dx.doi.org/10.1093/gerona/glab172

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