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Chemogenetic Disconnection between the Orbitofrontal Cortex and the Rostromedial Caudate Nucleus Disrupts Motivational Control of Goal-Directed Action

The orbitofrontal cortex (OFC) and its major downstream target within the basal ganglia—the rostromedial caudate nucleus (rmCD)—are involved in reward-value processing and goal-directed behavior. However, a causal contribution of the pathway linking these two structures to goal-directed behavior has...

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Detalles Bibliográficos
Autores principales: Oyama, Kei, Hori, Yukiko, Mimura, Koki, Nagai, Yuji, Eldridge, Mark A. G., Saunders, Richard C., Miyakawa, Naohisa, Hirabayashi, Toshiyuki, Hori, Yuki, Inoue, Ken-ichi, Suhara, Tetsuya, Takada, Masahiko, Higuchi, Makoto, Richmond, Barry J., Minamimoto, Takafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374131/
https://www.ncbi.nlm.nih.gov/pubmed/35794012
http://dx.doi.org/10.1523/JNEUROSCI.0229-22.2022