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Deployment of Sulfinimines in Charge-Accelerated Sulfonium Rearrangement Enables a Surrogate Asymmetric Mannich Reaction

[Image: see text] β-Amino acid derivatives are key structural elements in synthetic and biological chemistry. Despite being a hallmark method for their preparation, the direct Mannich reaction encounters significant challenges when carboxylic acid derivatives are employed. Indeed, not only is chemos...

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Detalles Bibliográficos
Autores principales: Feng, Minghao, Mosiagin, Ivan, Kaiser, Daniel, Maryasin, Boris, Maulide, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374180/
https://www.ncbi.nlm.nih.gov/pubmed/35839521
http://dx.doi.org/10.1021/jacs.2c05368