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Nicotinic receptor components of amyloid beta 42 proteome regulation in human neural cells

Alzheimer’s disease (AD) is associated with chronic neurodegeneration often accompanied by elevated levels of the neurotoxic peptide amyloid-beta 1–42 (Aβ(42)) in the brain. Studies show that extracellular Aβ(42) binds to various cell surface receptors including the human α7 nicotinic acetylcholine...

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Detalles Bibliográficos
Autores principales: Sinclair, Patricia, Kabbani, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374227/
https://www.ncbi.nlm.nih.gov/pubmed/35960729
http://dx.doi.org/10.1371/journal.pone.0270479