Mutant KRAS regulates transposable element RNA and innate immunity via KRAB zinc-finger genes

RAS genes are the most frequently mutated oncogenes in cancer, yet the effects of oncogenic RAS signaling on the noncoding transcriptome remain unclear. We analyzed the transcriptomes of human airway and bronchial epithelial cells transformed with mutant KRAS to define the landscape of KRAS-regulate...

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Detalles Bibliográficos
Autores principales: Reggiardo, Roman E., Maroli, Sreelakshmi Velandi, Halasz, Haley, Ozen, Mehmet, Hrabeta-Robinson, Eva, Behera, Amit, Peddu, Vikas, Carrillo, David, LaMontagne, Erin, Whitehead, Lila, Kim, Eejung, Malik, Shivani, Fernandes, Jason, Marinov, Georgi, Collisson, Eric, Brooks, Angela, Demirci, Utkan, Kim, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374308/
https://www.ncbi.nlm.nih.gov/pubmed/35858545
http://dx.doi.org/10.1016/j.celrep.2022.111104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374308/
https://www.ncbi.nlm.nih.gov/pubmed/35858545
http://dx.doi.org/10.1016/j.celrep.2022.111104

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