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C11orf94/Frey is a key regulator for male fertility by controlling Izumo1 complex assembly

Although gamete fusion represents the central event in sexual reproduction, the required protein machinery is poorly defined. In sperm cells, Izumo1 and several Izumo1-associated proteins play an essential role for this process. However, so far, the mechanisms underlying transport and maturation of...

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Detalles Bibliográficos
Autores principales: Contreras, Whendy, Wiesehöfer, Caroline, Schreier, Dora, Leinung, Nadja, Peche, Petra, Wennemuth, Gunther, Gentzel, Marc, Schröder, Bernd, Mentrup, Torben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374335/
https://www.ncbi.nlm.nih.gov/pubmed/35960805
http://dx.doi.org/10.1126/sciadv.abo6049