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A molecularly defined D1 medium spiny neuron subtype negatively regulates cocaine addiction

The striatum plays a critical role in regulating addiction-related behaviors. The conventional dichotomy model suggests that striatal D1/D2 medium spiny neurons (MSNs) positively/negatively regulate addiction-related behaviors. However, this model does not account for the neuronal heterogeneity and...

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Detalles Bibliográficos
Autores principales: Zhao, Zheng-dong, Han, Xiao, Chen, Renchao, Liu, Yiqiong, Bhattacherjee, Aritra, Chen, Wenqiang, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374336/
https://www.ncbi.nlm.nih.gov/pubmed/35960793
http://dx.doi.org/10.1126/sciadv.abn3552