Uncovering the universality of self-replication in protein aggregation and its link to disease

Fibrillar protein aggregates are a hallmark of a range of human disorders, from prion diseases to dementias, but are also encountered in several functional contexts. Yet, the fundamental links between protein assembly mechanisms and their functional or pathological roles have remained elusive. Here,...

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Detalles Bibliográficos
Autores principales: Meisl, Georg, Xu, Catherine K., Taylor, Jonathan D., Michaels, Thomas C. T., Levin, Aviad, Otzen, Daniel, Klenerman, David, Matthews, Steve, Linse, Sara, Andreasen, Maria, Knowles, Tuomas P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374340/
https://www.ncbi.nlm.nih.gov/pubmed/35960802
http://dx.doi.org/10.1126/sciadv.abn6831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374340/
https://www.ncbi.nlm.nih.gov/pubmed/35960802
http://dx.doi.org/10.1126/sciadv.abn6831

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