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Uncovering the universality of self-replication in protein aggregation and its link to disease
Fibrillar protein aggregates are a hallmark of a range of human disorders, from prion diseases to dementias, but are also encountered in several functional contexts. Yet, the fundamental links between protein assembly mechanisms and their functional or pathological roles have remained elusive. Here,...
Autores principales: | Meisl, Georg, Xu, Catherine K., Taylor, Jonathan D., Michaels, Thomas C. T., Levin, Aviad, Otzen, Daniel, Klenerman, David, Matthews, Steve, Linse, Sara, Andreasen, Maria, Knowles, Tuomas P. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374340/ https://www.ncbi.nlm.nih.gov/pubmed/35960802 http://dx.doi.org/10.1126/sciadv.abn6831 |
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