Supercharged chimeric antigen receptor T cells in solid tumors

Chimeric antigen receptor (CAR) T cells have demonstrated success in treating select hematological malignancies, but their activity in solid tumors has been comparably modest. Challenges specific to treating solid tumors include trafficking and distribution throughout the tumor site, overcoming the...

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Detalles Bibliográficos
Autores principales: Pant, Ayush, Jackson, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374370/
https://www.ncbi.nlm.nih.gov/pubmed/35968786
http://dx.doi.org/10.1172/JCI162322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374370/
https://www.ncbi.nlm.nih.gov/pubmed/35968786
http://dx.doi.org/10.1172/JCI162322

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