The NCF1 variant p.R90H aggravates autoimmunity by facilitating the activation of plasmacytoid dendritic cells

Plasmacytoid dendritic cells (pDCs) are a professional type I IFN producer that play critical roles in the pathogenesis of autoimmune diseases. However, both genetic regulation of the function of pDCs and their relationships with autoimmunity are largely undetermined. Here, we investigated the causa...

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Detalles Bibliográficos
Autores principales: Meng, Yao, Ma, Jianyang, Yao, Chao, Ye, Zhizhong, Ding, Huihua, Liu, Can, Li, Jun, Li, Guanhua, He, Yuke, Li, Jia, Yin, Zhihua, Wu, Li, Zhou, Haibo, Shen, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374378/
https://www.ncbi.nlm.nih.gov/pubmed/35788118
http://dx.doi.org/10.1172/JCI153619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374378/
https://www.ncbi.nlm.nih.gov/pubmed/35788118
http://dx.doi.org/10.1172/JCI153619

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