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CXCR4(high) megakaryocytes regulate host-defense immunity against bacterial pathogens

Megakaryocytes (MKs) continuously produce platelets to support hemostasis and form a niche for hematopoietic stem cell maintenance in the bone marrow. MKs are also involved in inflammatory responses; however, the mechanism remains poorly understood. Using single-cell sequencing, we identified a CXCR...

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Detalles Bibliográficos
Autores principales: Wang, Jin, Xie, Jiayi, Wang, Daosong, Han, Xue, Chen, Minqi, Shi, Guojun, Jiang, Linjia, Zhao, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374440/
https://www.ncbi.nlm.nih.gov/pubmed/35904250
http://dx.doi.org/10.7554/eLife.78662