Cargando…
CXCR4(high) megakaryocytes regulate host-defense immunity against bacterial pathogens
Megakaryocytes (MKs) continuously produce platelets to support hemostasis and form a niche for hematopoietic stem cell maintenance in the bone marrow. MKs are also involved in inflammatory responses; however, the mechanism remains poorly understood. Using single-cell sequencing, we identified a CXCR...
Autores principales: | Wang, Jin, Xie, Jiayi, Wang, Daosong, Han, Xue, Chen, Minqi, Shi, Guojun, Jiang, Linjia, Zhao, Meng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374440/ https://www.ncbi.nlm.nih.gov/pubmed/35904250 http://dx.doi.org/10.7554/eLife.78662 |
Ejemplares similares
-
Host autophagy machinery is diverted to the pathogen interface to mediate focal defense responses against the Irish potato famine pathogen
por: Dagdas, Yasin F, et al.
Publicado: (2018) -
Divalent Metal Uptake and the Role of ZIP8 in Host Defense Against Pathogens
por: Samuelson, Derrick R., et al.
Publicado: (2022) -
In vitro Generation of Megakaryocytes and Platelets
por: Liu, Huicong, et al.
Publicado: (2021) -
Genome Editing Technologies as Cellular Defense Against Viral Pathogens
por: Zhang, Yingzi, et al.
Publicado: (2021) -
Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets
por: Cunin, Pierre, et al.
Publicado: (2019)