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Integrative small and long RNA omics analysis of human healing and nonhealing wounds discovers cooperating microRNAs as therapeutic targets

MicroRNAs (miR), as important epigenetic control factors, reportedly regulate wound repair. However, our insufficient knowledge of clinically relevant miRs hinders their potential therapeutic use. For this, we performed paired small and long RNA-sequencing and integrative omics analysis in human tis...

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Detalles Bibliográficos
Autores principales: Liu, Zhuang, Zhang, Letian, Toma, Maria A, Li, Dongqing, Bian, Xiaowei, Pastar, Irena, Tomic-Canic, Marjana, Sommar, Pehr, Xu Landén, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374442/
https://www.ncbi.nlm.nih.gov/pubmed/35942686
http://dx.doi.org/10.7554/eLife.80322