Cargando…

miR-99a-5p: A Potential New Therapy for Atherosclerosis by Targeting mTOR and Then Inhibiting NLRP3 Inflammasome Activation and Promoting Macrophage Autophagy

OBJECTIVE: MicroRNAs have been revealed to be involved in the development of atherosclerosis. The present study is aimed at exploring the potential of miR-99a-5p as a therapy for atherosclerosis. We suspected that miR-99a-5p might inhibit NLRP3 inflammasome activation and promote macrophage autophag...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Gang, Jing, Shu-Yan, Liu, Gang, Guo, Xue-Jia, Zhao, Wei, Jia, Xin-Le, Zheng, Ming-Qi, Tan, Wen-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374553/
https://www.ncbi.nlm.nih.gov/pubmed/35968506
http://dx.doi.org/10.1155/2022/7172583