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Naringenin potentiates anti-tumor immunity against oral cancer by inducing lymph node CD169-positive macrophage activation and cytotoxic T cell infiltration

The CD169(+) macrophages in lymph nodes are implicated in cytotoxic T lymphocyte (CTL) activation and are associated with improved prognosis in several malignancies. Here, we investigated the significance of CD169(+) macrophages in oral squamous cell carcinoma (OSCC). Further, we tested the anti-tum...

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Detalles Bibliográficos
Autores principales: Kawaguchi, Sho, Kawahara, Kenta, Fujiwara, Yukio, Ohnishi, Koji, Pan, Cheng, Yano, Hiromu, Hirosue, Akiyuki, Nagata, Masashi, Hirayama, Masatoshi, Sakata, Junki, Nakashima, Hikaru, Arita, Hidetaka, Yamana, Keisuke, Gohara, Shunsuke, Nagao, Yuka, Maeshiro, Manabu, Iwamoto, Asuka, Hirayama, Mayumi, Yoshida, Ryoji, Komohara, Yoshihiro, Nakayama, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374624/
https://www.ncbi.nlm.nih.gov/pubmed/35044489
http://dx.doi.org/10.1007/s00262-022-03149-w