A life history model of the ecological and evolutionary dynamics of polyaneuploid cancer cells

Therapeutic resistance is one of the main reasons for treatment failure in cancer patients. The polyaneuploid cancer cell (PACC) state has been shown to promote resistance by providing a refuge for cancer cells from the effects of therapy and by helping them adapt to a variety of environmental stres...

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Detalles Bibliográficos
Autores principales: Bukkuri, Anuraag, Pienta, Kenneth J., Austin, Robert H., Hammarlund, Emma U., Amend, Sarah R., Brown, Joel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374668/
https://www.ncbi.nlm.nih.gov/pubmed/35962062
http://dx.doi.org/10.1038/s41598-022-18137-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374668/
https://www.ncbi.nlm.nih.gov/pubmed/35962062
http://dx.doi.org/10.1038/s41598-022-18137-4

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