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Nicotinamide mononucleotide ameliorates adriamycin-induced renal damage by epigenetically suppressing the NMN/NAD consumers mediated by Twist2

The activation of nicotinamide adenine dinucleotide (NAD(+))-dependent deacetylase, Sirt1, after the administration of nicotinamide mononucleotide (NMN) suppresses many diseases. However, the role of NMN and Sirt1 in focal glomerulosclerosis (FSGS) has not yet been elucidated. This study aimed to as...

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Detalles Bibliográficos
Autores principales: Hasegawa, Kazuhiro, Sakamaki, Yusuke, Tamaki, Masanori, Wakino, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374671/
https://www.ncbi.nlm.nih.gov/pubmed/35962139
http://dx.doi.org/10.1038/s41598-022-18147-2