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Selective binding and transport of protocadherin 15 isoforms by stereocilia unconventional myosins in a heterologous expression system

During hair cell development, the mechanoelectrical transduction (MET) apparatus is assembled at the stereocilia tips, where it coexists with the stereocilia actin regulatory machinery. While the myosin-based tipward transport of actin regulatory proteins is well studied, isoform complexity and buil...

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Detalles Bibliográficos
Autores principales: Ballesteros, Angela, Yadav, Manoj, Cui, Runjia, Kurima, Kiyoto, Kachar, Bechara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374675/
https://www.ncbi.nlm.nih.gov/pubmed/35962067
http://dx.doi.org/10.1038/s41598-022-17757-0