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Selective binding and transport of protocadherin 15 isoforms by stereocilia unconventional myosins in a heterologous expression system
During hair cell development, the mechanoelectrical transduction (MET) apparatus is assembled at the stereocilia tips, where it coexists with the stereocilia actin regulatory machinery. While the myosin-based tipward transport of actin regulatory proteins is well studied, isoform complexity and buil...
Autores principales: | Ballesteros, Angela, Yadav, Manoj, Cui, Runjia, Kurima, Kiyoto, Kachar, Bechara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374675/ https://www.ncbi.nlm.nih.gov/pubmed/35962067 http://dx.doi.org/10.1038/s41598-022-17757-0 |
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