Acidosis induces RIPK1-dependent death of glioblastoma stem cells via acid-sensing ion channel 1a

Eliciting regulated cell death, like necroptosis, is a potential cancer treatment. However, pathways eliciting necroptosis are poorly understood. It has been reported that prolonged activation of acid-sensing ion channel 1a (ASIC1a) induces necroptosis in mouse neurons. Glioblastoma stem cells (GSCs...

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Detalles Bibliográficos
Autores principales: Clusmann, Jan, Franco, Klaus-Daniel Cortés, Suárez, David Alejandro Corredor, Katona, Istvan, Minguez, Maria Girbes, Boersch, Nina, Pissas, Karolos-Philippos, Vanek, Jakob, Tian, Yuemin, Gründer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374719/
https://www.ncbi.nlm.nih.gov/pubmed/35961983
http://dx.doi.org/10.1038/s41419-022-05139-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374719/
https://www.ncbi.nlm.nih.gov/pubmed/35961983
http://dx.doi.org/10.1038/s41419-022-05139-3

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