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Acidosis induces RIPK1-dependent death of glioblastoma stem cells via acid-sensing ion channel 1a
Eliciting regulated cell death, like necroptosis, is a potential cancer treatment. However, pathways eliciting necroptosis are poorly understood. It has been reported that prolonged activation of acid-sensing ion channel 1a (ASIC1a) induces necroptosis in mouse neurons. Glioblastoma stem cells (GSCs...
Autores principales: | Clusmann, Jan, Franco, Klaus-Daniel Cortés, Suárez, David Alejandro Corredor, Katona, Istvan, Minguez, Maria Girbes, Boersch, Nina, Pissas, Karolos-Philippos, Vanek, Jakob, Tian, Yuemin, Gründer, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374719/ https://www.ncbi.nlm.nih.gov/pubmed/35961983 http://dx.doi.org/10.1038/s41419-022-05139-3 |
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