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Identification of a BRAF/PA28γ/MEK1 signaling axis and its role in epithelial-mesenchymal transition in oral submucous fibrosis

Oral submucous fibrosis (OSF) is a chronic and insidious oral potentially malignant disorder associated with a 4–17% risk of oral squamous cell carcinoma (OSCC). Our previous study found that proteasomal activator 28 gamma (PA28γ) is frequently overexpressed in oral squamous cell carcinoma and negat...

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Detalles Bibliográficos
Autores principales: Xie, Changqing, Li, Zaiye, Hua, Yufei, Sun, Silu, Zhong, Liang, Chen, Qian, Feng, Hui, Ji, Ning, Li, Taiwen, Zhou, Xikun, Zeng, Xin, Tang, Zhangui, Sun, Chongkui, Li, Jing, Chen, Qianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374740/
https://www.ncbi.nlm.nih.gov/pubmed/35961969
http://dx.doi.org/10.1038/s41419-022-05152-6