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Absolute protein quantitation of the mouse macrophage Toll-like receptor and chemotaxis pathways

The Toll-like receptor (TLR) and chemotaxis pathways are key components of the innate immune system. Subtle variation in the concentration, timing, and molecular structure of the ligands are known to affect downstream signaling and the resulting immune response. Computational modeling and simulation...

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Detalles Bibliográficos
Autores principales: Manes, Nathan P., Calzola, Jessica M., Kaplan, Pauline R., Fraser, Iain D. C., Germain, Ronald N., Meier-Schellersheim, Martin, Nita-Lazar, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374760/
https://www.ncbi.nlm.nih.gov/pubmed/35961990
http://dx.doi.org/10.1038/s41597-022-01612-y